EURATRANS

European large-scale functional genomics in the rat for translational research

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats.

publication in Nature Genetics, 21(16), 3546-57 (2013)

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RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing

publication in Nature Medicine,18, 766-773 (2012)

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Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function

publication in Natue, 478(7367), 114-118 (2011)

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Science Magazine Breakthrough of the Year: Knockout rats are runner up!

Science Vol. 330. No 6011, p. 1605, NEWS FOCUS

Knockout rats are among the runners up of Science Magazine's Breakthrough of the Year selection. This acknowledges the recent development in zink finger nuclease, knockout and transposon technologies which could mean that "knockout and genetically modified rats may soon displace their smaller cousins in lab cages around the world".


 

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

publication in Nature, 467(7314), 460-464 (2010)

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Science Magazine News: One-Two Punch Elevates Rats to the Knockout Ranks

Science Vol. 329. No 5994, p. 892 NEWS OF THE WEEK

Science Magazine NEWS OF THE WEEK on the latest developments in knockout rat technologies. Dennis Normile interviewed Tim Aitman (Imperial College London) and refers to Aron Geurths' work with Zink Finger Nuclease technolgy (Medical College of Wisconsin, Milwaukee) and Zsuzsanna Izsvaks' work with transposons (Max Delbrück Center for Molecular Medicine, Berlin), all of them Principal Investigators in the EURATRANS consortium.  

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jaune EURATRANS is co-funded by the European Community‘s Seventh Framework Programme (FP7/2007-2013) under grant agreement N° HEALTH-F4-2010-241504. FP7-coo-RGB
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